HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68411844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68411553 | HCID 68411553 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Triethylsilane | HCID 12052 | — |
| Product | HCID 68411844 | HCID 68411844 | 88.2% |
Reaction Steps
Compound 133 (915 mg, 1.417 mmol) was dissolved in dichloromethane (20 mL) and triethylsilane (0.56 mL). TFA (20 ml) was added dropwise at room temperature and the mixture was left for 3 h at room temperature. Removal of the solvent gave the title compound (737 mg, 88%) MS (M+H)+ 590.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659245B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-6ad5030f4ecb4f959fb237549ae1c005 |
| Source note | uspto-grants-2010_02 |