HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68410975, compound → HCID 68410363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68410975 | HCID 68410975 | — |
| Catalyst | (1,3-Bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene)(dichloro)((2-((propan-2-yl)oxy)phenyl)methylidene)ruthenium | HCID 11763533 | — |
| Product | HCID 68410363 | HCID 68410363 | 75% |
Reaction Steps
The diene 135 (585 mg, 0.854 mmol) and Hoveyda-Grubbs catalyst, IInd generation (50 mg) were dissolved in degassed and dry 1,2-dichloroethane (500 mL). The mixture was heated to reflux temperature over-night under argon atmosphere. Evaporation of the solvent and purification by column chromatography (silica gel; Heptane/EtOAc 70:30) gave the title compound (420 mg, 75%). MS (M+H)+ 658.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659245B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-3d2d63e0b99b4957afb9d3e733ac3585 |
| Source note | uspto-grants-2010_02 |