Dichloromethane → tert-butyl N-[1-[2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl]pyrrolidin-3-yl]carbamate
Reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[Cl:21][c:22]1[n:23][c:24](-[c:33]2[c:34]([OH:40])[cH:35][cH:36][cH:37][c:38]2[F:39])[n:25][c:26]2[cH:27][c:28]([CH3:32])[cH:29][cH:30][c:31]12.[Cl:41][CH2:42][Cl:43].[NH:1]1[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1>>[N:1]1([c:22]2[n:23][c:24](-[c:33]3[c:34]([OH:40])[cH:35][cH:36][cH:37][c:38]3[F:39])[n:25][c:26]3[cH:27][c:28]([CH3:32])[cH:29][cH:30][c:31]23)[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1Participants
5
Sources & evidence
- ORD record
- ord-7c05ab405ddc422f9ab19aca2abb79b2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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