Hydrochloric Acid → HCID 58879049, Verbindung

HRID 1443588Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1443588
[F:1][C:2]([F:13])([C:9]([F:12])([F:11])[F:10])[CH2:3][CH:4]([C:7]#[N:8])[C:5]#[N:6].I[CH2:15][CH2:16][C:17]([F:26])([F:25])[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20].C(=O)([O-])[O-].[K+].[K+].Cl>CC(C)=O>[F:25][C:17]([F:26])([C:18]([F:23])([F:24])[C:19]([F:20])([F:21])[F:22])[CH2:16][CH2:15][C:4]([CH2:3][C:2]([F:13])([F:1])[C:9]([F:10])([F:11])[F:12])([C:7]#[N:8])[C:5]#[N:6]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 109697Alkyl iodides, C4-20, gamma-omega-perfluoroHCID 866125702-(2,2,3,3,3-Pentafluoropropyl)malononitrile

Produkt 1

HCID 58879049HCID 58879049, VerbindungAusbeute 0,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

In 50 ml of acetone, 3.2 g of 2-(2,2,3,3,3-pentafluoropropyl)malononitrile and 7.2 g of 5-iodo-1,1,1,2,2,3,3-heptafluoropentane were dissolved, 3.2 g of potassium carbonate was added and the mixture was stirred at room temperature for 10 hours. Thereafter, dilute hydrochloric acid was added to the reaction mixture and the mixture was extracted with t-butyl methyl ether. The organic layer was washed successively with water, aqueous saturated sodium hydrogen carbonate and aqueous saturated sodium chloride, dried over anhydrous magnesium sulfate, and then concentrated under reduced pressure. The residue was subjected to silica gel column chromatography to obtain 0.05 g of 2-(3,3,4,4,5,5,5-heptafluoropentyl)-2-(2,2,3,3,3-pentafluoropropyl)malononitrile (hereinafter, referred to as the present compound (96)):

Aufarbeitung

  1. extractionthe mixture was extracted with t-butyl methyl ether
  2. washThe organic layer was washed successively with water, aqueous saturated sodium hydrogen carbonate and aqueous saturated sodium chloride
  3. dry with materialdried over anhydrous magnesium sulfate
  4. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-eefc2ac2d1244872bf884ea02f262c29
Quelldatensatz
uspto-grants-2010_02
Patentnummer
US07662402B2

Notizen zur Reaktion

Wird geladen…