Boron tribromide → HCID 136206536, compound

Participants

Reaction Steps

Using a method similar to that described in Example 165, 5-[2-(2-methoxy-phenyl)-oxazol-4-yl]-pentanoic acid methyl ester (1.65 g, 5.7 mmol) with boron tribromide (1.0 M in CH2Cl2, 17.2 m/L) in CH2Cl2 gives 5-[2-(2-hydroxy-phenyl)-oxazol-4-yl]-pentanoic acid methyl ester (0.76 g, 48%). MS (ES): (M+1)+ 276.1, 277.2 m/z.

Provenance & Evidence