HCID 67442555, compound → HCID 67441600, compound

HRID 1443770Notes

Reaction equation

HRID 1443770 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH:16]3[CH2:17][CH2:18][N:13]([CH2:14][CH2:15]3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O>[Pd].CO>[N:13]12[CH2:18][CH2:17][CH:16]([CH2:15][CH2:14]1)[N:10]([C:7]1[CH:8]=[CH:9][C:4]([NH2:1])=[CH:5][CH:6]=1)[CH2:11][CH2:12]2

Participants

4

Reactant 1

HCID 67442555HCID 67442555, compound

Product 1

HCID 67441600HCID 67441600, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 4-(4-nitrophenyl)-1,4-diaza-bicyclo[3.2.2]nonane (0.50 g, 2.0 mmol), palladium on carbon (100 mg, 10%) and methanol (60 ml) was stirred for 15 minutes under hydrogen (130 ml of hydrogen was consumed). The crude mixture was filtered through celite and the product was isolated as an oil in quantitative yield.

Workup

  1. filtrationThe crude mixture was filtered through celite
  2. customthe product was isolated as an oil in quantitative yield

Sources & evidence

ORD record
ord-9ab75ab9fbbd4a4989d928ef965e6db2
Source dataset
uspto-grants-2010_02
Patent number
US07662808B2

Reaction notes

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