反应详情

Following the procedure of Example 1, Step 1, cyclooctanone (6.9 mL, 52 mmol), 1-aminoindoline (7.0 g, 52 mmol) and concentrated sulfuric acid (10 mL) in water (90 mL) provided 4,5,7,8,9,10,11,12-octahydrocycloocta[b]pyrrolo[3,2,1-hi]indole (3.6 g). MS (ES) m/z 226.2.