Dimethylamine → HCID 10126912, compound

HRID 1443988Notes

Reaction equation

HRID 1443988 reaction equation
[CH3:1][NH:2][CH3:3].[Cl:4][C:5]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:6]=1[S:12]([N:15]([C:24]1[C:29]([O:30][CH3:31])=[N:28][C:27](Cl)=[C:26]([Cl:33])[N:25]=1)COCC[Si](C)(C)C)(=[O:14])=[O:13]>O1CCCC1>[Cl:4][C:5]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:6]=1[S:12]([NH:15][C:24]1[C:29]([O:30][CH3:31])=[N:28][C:27]([N:2]([CH3:3])[CH3:1])=[C:26]([Cl:33])[N:25]=1)(=[O:13])=[O:14]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 11180148HCID 11180148, compound

Product 1

HCID 10126912HCID 10126912, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared by the method of Example 67 using dimethylamine (5 mL of a 2M solution in tetrahydrofuran) and 2,3-dichloro-N-(5,6-dichloro-3-methoxy-2-pyrazinyl)-N-{[2-(trimethylsilyl)ethoxy]methyl}benzenesulfonamide (0.1 g). Yield 0.015g.

Sources & evidence

ORD record
ord-733ea0e5a90c4cb98f74449456c5d31e
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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