HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanol → HCID 59168095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanol | HCID 7510 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Amino-3-chloropyrazine | HCID 276224 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 59168095 | HCID 59168095 | 79.7% |
Reaction Steps
Prepared as for Example 121a using 3-chloro-2-aminopyrazine (0.5 g), pyridine-3-methanol (0.42 g) and sodium hydride (0.31 g of a 60% dispersion in oil) in N-methylpyrrolidinone (5 mL) to afford the sub-titled compound as a solid (0.62 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662825B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-06c2536f581d42fbbf532cb7173b86be |
| Source note | uspto-grants-2010_02 |