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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444034Generated: October 31, 2026

2-Amino-3-chloropyrazine → HCID 59168142, compound

https://huagongshe.com/reaction/1444034

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-3-chloropyrazineHCID 276224—
Reactant3-Fluorobenzenesulfonyl ChlorideHCID 2734258—
ReactantSodium MethoxideHCID 10942334—
SolventMethanolHCID 887—
ProductHCID 59168142HCID 59168142—

Reaction Steps

By the method outlined in Example 1 (reaction performed at room temperature) using 3-chloro-2-pyrazinamine (1.29 g), 3-fluorobenzenesulphonyl chloride (2.13 g). The crude adduct was reacted with a solution of sodium methoxide (10 mL of a 25% solution in methanol) in methanol (20 mL) to afford the sub-titled compound (2.36 g) as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662825B2
Source datasetuspto-grants-2010_02
ORD IDord-f1167fc1edd34e9f904a9fd9dfe24fe7
Source noteuspto-grants-2010_02