HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Pyridinedimethanol → 2,3-Dichloro-N-[5-chloro-3-{[6-(hydroxymethyl)-2-pyridinyl]methoxy}-2-pyrazinyl]benzenesulphonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Pyridinedimethanol | HCID 70957 | — |
| Reactant | 2,3-dichloro-N-(3,5-dichloro-2-pyrazinyl)benzenesulphonamide | HCID 10126340 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 2,3-Dichloro-N-[5-chloro-3-{[6-(hydroxymethyl)-2-pyridinyl]methoxy}-2-pyrazinyl]benzenesulphonamide | HCID 59168143 | — |
Reaction Steps
Prepared by the method of Example 31 using 2,6-bis(hydroxymethyl)pyridine (0.11 g) and 2,3-dichloro-N-(3,5-dichloro-2-pyrazinyl)benzenesulphonamide (Example 74) (0.11 g) in N-methylpyrrolidinone (2 mL). Yield 0.043 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662825B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-9d8b66e27b574eb4a11cfa6026cd6402 |
| Source note | uspto-grants-2010_02 |