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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444080Generated: October 31, 2026

N,N-Diethyl-2-hydroxyacetamide → 2-[5-(2,3-Dichlorobenzenesulphonylamino)-6-methoxy-2-pyrazinyloxy]-N,N-diethyl-acetamide

https://huagongshe.com/reaction/1444080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Diethyl-2-hydroxyacetamideHCID 4137580—
ReactantN-(5-Bromo-3-methoxy-2-pyrazinyl)-2,3-dichloro-N-[{2-(trimethylsilanyl)ethoxy}methyl]benzenesulphonamideHCID 59168156—
Product2-[5-(2,3-Dichlorobenzenesulphonylamino)-6-methoxy-2-pyrazinyloxy]-N,N-diethyl-acetamideHCID 59168182—

Reaction Steps

Prepared as for Example 115b using N-(5-bromo-3-methoxy-2-pyrazinyl)-2,3-dichloro-N-[{2-(trimethylsilanyl)ethoxy}methyl]benzenesulphonamide (Example 55a) (0.35 g) and N,N-diethyl-2-hydroxyacetamide (0.13 g). Yield 0.2 g

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662825B2
Source datasetuspto-grants-2010_02
ORD IDord-75223415f55d4deabca37174cf3452b3
Source noteuspto-grants-2010_02