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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1444096Generated: October 25, 2026

Benzaldehyde → N-Benzylidene(piperidin-4-yl)methanamine

https://huagongshe.com/reaction/1444096

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant4-(Aminomethyl)piperidineHCID 23527—
SolventTolueneHCID 1140—
ProductN-Benzylidene(piperidin-4-yl)methanamineHCID 11820173—

Reaction Steps

Benzaldehyde (4.6 g; 0.044 mol) was added dropwise to a solution of 4-aminomethylpiperidine (5.0 g; 0.044 mol) in toluene (20 ml). The solution thus obtained was stirred for 3 h at room temperature. Then the solvent was removed by evaporation at reduced pressure and the residue was taken up twice with toluene to give the desired product that was used as such without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07662836B2
Source datasetuspto-grants-2010_02
ORD IDord-5924d5348ad944b5b28619e072e9943f
Source noteuspto-grants-2010_02