HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-D-Tyr(Me)-L-Ile-L-Pro-OBzl → Boc-D-Tyr(Me)-L-Ile-L-Pro-OH
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-D-Tyr(Me)-L-Ile-L-Pro-OBzl | HCID 131727885 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Boc-D-Tyr(Me)-L-Ile-L-Pro-OH | HCID 131727886 | — |
Reaction Steps
Boc-D-Tyr(Me)-L-Ile-L-Pro-OBzl (595 mg, 1.0 mmol) was dissolved in methanol (10 mL), Pd—C (200 mg) was added, and this mixture was stirred under hydrogen atmosphere for 3 hours. Pd—C was filtered off, and methanol was removed by evaporation to obtain the desired product as a foam. Yield: 380 mg (0.8 mmol, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07662778B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-ff1eaa7180b44662bb4dae00a2f411a7 |
| Source note | uspto-grants-2010_02 |