Hydrochloric Acid → HCID 66905855, compound

HRID 1444302Notes

Reaction equation

HRID 1444302 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:14]=[CH:15][CH:16]=1)[CH:7]=[C:8]([CH2:12][CH3:13])[C:9]([OH:11])=[O:10])([O-:3])=[O:2].Cl.[CH3:18][CH2:19]O>>[CH2:18]([O:10][C:9](=[O:11])[C:8](=[CH:7][C:6]1[CH:14]=[CH:15][CH:16]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)[CH2:12][CH3:13])[CH3:19]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 990102-[(3-Nitrophenyl)methylene]butanoic acid

Product 1

HCID 66905855HCID 66905855, compound

Procedure

2-(3-Nitro-benzylidene)-butyric acid (500 mg, 2.27 mmol) was esterified by dissolving in EtOH (12.5 ml), adding conc HCl (0.25 ml) and heating to reflux for 8 h. The solvents were evaporated in vacuo to give the title compound.

Workup

  1. temperatureheating
  2. temperatureto reflux for 8 h
  3. customThe solvents were evaporated in vacuo

Sources & evidence

ORD record
ord-817c179eddcc4322bd65e6567d67fd97
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Reaction notes

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