ethyl-E-4-(3-methoxyphenyl)-4-methylpent-2-enoate → Ethyl-4-(3-methoxyphenyl)-4-methylpentanoate

HRID 1444535Notes

Reaction equation

HRID 1444535 reaction equation
[CH2:1]([O:3][C:4](=[O:18])/[CH:5]=[CH:6]/[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[CH:11]=1)([CH3:9])[CH3:8])[CH3:2]>C(OCC)(=O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][CH2:6][C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[CH:11]=1)([CH3:8])[CH3:9])[CH3:2]

Participants

4

Reactant 1

HCID 86599931ethyl-E-4-(3-methoxyphenyl)-4-methylpent-2-enoate

Product 1

HCID 17989275Ethyl-4-(3-methoxyphenyl)-4-methylpentanoate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

27.2 g (109.5 mmol) of ethyl-E-4-(3-methoxyphenyl)-4-methylpent-2-enoate is mixed in 293 ml of ethyl acetate with 2.72 g of palladium on carbon (10%) and stirred under hydrogen atmosphere for 18 hours at room temperature. The catalyst is removed by filtration through a glass-fiber filter, and the residue that remains after the concentration by evaporation (27.2 g=99.2%) is incorporated in crude form into the next stage.

Workup

  1. customThe catalyst is removed by filtration through a glass-fiber
  2. filtrationfilter
  3. concentrationafter the concentration
  4. customby evaporation (27.2 g=99.2%)

Sources & evidence

ORD record
ord-e5253f423aba4fc1a98677e9c8f8967a
Source dataset
uspto-grants-2010_02
Patent number
US07662821B2

Reaction notes

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