Hydrochloric Acid → HCID 59025529, compound

Participants

Reaction Steps

24 mg of the compound from Example 22 (0.04 mol) are dissolved in 2.0 ml of THF/methanol (1:1). 0.1 ml of 1 N sodium hydroxide solution is added, and the reaction mixture is stirred at room temperature for 16 h. It is diluted with water and acidified with 1 N hydrochloric acid, and the mixture is extracted three times with dichloromethane. The combined organic phases are dried over sodium sulphate, and the solvent is removed in a rotary evaporator. 23 mg (100% of theory) of the title compound are obtained.

Provenance & Evidence