4-Fluorobenzylamine → HCID 43152711, compound

HRID 1445013Notes

Reaction equation

HRID 1445013 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[N:3]=1.[F:12][C:13]1[CH:20]=[CH:19][C:16]([CH2:17][NH2:18])=[CH:15][CH:14]=1>>[Cl:11][C:4]1[N:3]=[C:2]([NH:18][CH2:17][C:16]2[CH:19]=[CH:20][C:13]([F:12])=[CH:14][CH:15]=2)[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 852392,6-Dichloro-3-nitropyridine

Product 1

HCID 43152711HCID 43152711, compoundYield 65%

Procedure

In accordance with the same procedures as in Preparation 7, except for using 2,6-dichloro-3-nitropyridine and 4-fluorobenzylamine, the titled compound was obtained as yellow solid. (Yield: 65%)

Workup

  1. customIn accordance with the same procedures as in Preparation 7

Sources & evidence

ORD record
ord-9ec434f408414ac089f1f9641786dd40
Source dataset
uspto-grants-2010_02
Patent number
US07662832B2

Reaction notes

Loading…