4-Fluorobenzyl chloride → HCID 11701994, compound

HRID 1445049Notes

Reaction equation

HRID 1445049 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[NH:8][C:7]=12.[F:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Cl)=[CH:16][CH:15]=1>>[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:18][C:17]3[CH:20]=[CH:21][C:14]([F:13])=[CH:15][CH:16]=3)[C:7]=12

Participants

3

Reactant 2

HCID 96024-Fluorobenzyl chlorideHCID 116369277-Chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 11701994HCID 11701994, compoundYield 86%

Procedure

In accordance with the same procedures as in Step 2 of Example 198, except for using 7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 1 of Example 198 and 4-fluorobenzyl chloride, the titled compound was obtained as a pale yellow solid. (Yield: 86%)

Sources & evidence

ORD record
ord-283c4ea4bebf4295856d4a9439a5e7bb
Source dataset
uspto-grants-2010_02
Patent number
US07662832B2

Reaction notes

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