Benzyl Bromide → HCID 67141367, compound

HRID 1445136Notes

Reaction equation

HRID 1445136 reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[C:11]1[N:12]=[C:13]([C:21]#[N:22])[CH:14]=[C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][C:16]=12.[CH2:23](Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([N:17]1[C:16]2=[C:11]([N:2]3[CH2:3][CH2:4][C:5]4[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=4)[CH2:1]3)[N:12]=[C:13]([C:21]#[N:22])[CH:14]=[C:15]2[CH:19]=[C:18]1[CH3:20])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 67142144HCID 67142144, compound

Product 1

HCID 67141367HCID 67141367, compoundYield 87%

Procedure

In accordance with the same procedures as in Example 657, except for using 7-(3,4-dihydro-1H-isoquinolin-2-yl)-2-methyl-1H-pyrrolo[2,3-c]pyridin-5-carbonitrile prepared in Step 2 of Example 917 and benzyl bromide, the titled compound was obtained as a white solid. (Yield: 87%)

Sources & evidence

ORD record
ord-4363259909ae4fcab22853246753b934
Source dataset
uspto-grants-2010_02
Patent number
US07662832B2

Reaction notes

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