Methyl iodide → 4-(tert-butyl-dimethyl-silanyloxymethyl)-1-(4-fluoro-phenyl)-2-methyl-1H-imidazole
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([c:8]1[n:9][cH:10][n:11](-[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[cH:12]1)([CH3:20])[CH3:21].[CH2:22]([Li:23])[CH2:24][CH2:25][CH3:26].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[I:27][CH3:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([c:8]1[n:9][c:10]([CH3:22])[n:11](-[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[cH:12]1)([CH3:20])[CH3:21]Participants
5
Sources & evidence
- ORD record
- ord-25f406d910654443add7eec2713a7946
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…