HRID1445465

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

结构：C[C@@H]1CN(c2cc(F)c(C#N)c(F)c2)[C@@H](C)CN1

HCID68691962

4-[(2S,5R)-2,5-Dimethylpiperazin-1-yl]-2,6-difluorobenzonitrile

C13H15F2N3

PRODUCTS

生成物

结构：COc1cc(N2C[C@@H](C)NC[C@@H]2C)cc(F)c1C#N

HCID68691170

4-[(2S,5R)-2,5-Dimethylpiperazin-1-yl]-2-fluoro-6-methoxybenzonitrile

C14H18FN3O

PROCEDURE

实验过程

The compound was synthesized in the similar manner as in Reference Example 4-1 using 4-[(2S,5R)-2,5-dimethylpiperazin-1-yl]-2,6-difluorobenzonitrile and 1 equivalent of potassium tert-butoxide.