HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium tert-butoxide → 4-[(2S,5R)-2,5-dimethylpiperazin-1-yl]-2-fluoro-6-methoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | 4-[(2S,5R)-2,5-dimethylpiperazin-1-yl]-2,6-difluorobenzonitrile | HCID 68691962 | — |
| Product | 4-[(2S,5R)-2,5-dimethylpiperazin-1-yl]-2-fluoro-6-methoxybenzonitrile | HCID 68691170 | — |
Reaction Steps
The compound was synthesized in the similar manner as in Reference Example 4-1 using 4-[(2S,5R)-2,5-dimethylpiperazin-1-yl]-2,6-difluorobenzonitrile and 1 equivalent of potassium tert-butoxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666873B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-7b9d1084d72143e69bd75e255f03e409 |
| Source note | uspto-grants-2010_02 |