HCID 86621689, compound → HCID 15985349, compound

HRID 1445488Notes

Reaction equation

HRID 1445488 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:39])/[CH:16]=[CH:17]/[C:18]1[CH:22]=[CH:21][N:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[C:33]([CH3:38])=[N:34][O:35][C:36]=3[CH3:37])=[CH:28][CH:27]=2)(=[O:25])=[O:24])[CH:19]=1)(C)(C)C>O1CCOCC1>[NH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:39])/[CH:16]=[CH:17]/[C:18]1[CH:22]=[CH:21][N:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[C:33]([CH3:38])=[N:34][O:35][C:36]=3[CH3:37])=[CH:28][CH:27]=2)(=[O:25])=[O:24])[CH:19]=1

Participants

3

Reactant 1

HCID 86621689HCID 86621689, compound

Product 1

HCID 15985349HCID 15985349, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A mixture of 0.020 g [2-((E)-3-{1-[4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonyl]-1H-pyrrol-3-yl}-allanoylamino)-phenyl]-carbamic acid tert-butyl ester with a little amount of dioxane and 3 ml 4M HCL in dioxane is stirred at ambient temperature for 1 h. The suspension is centrifuged. The title compound is dried in vacuo. By this method 0.013 g of a red-brown amorph substance are obtained.

Workup

  1. dry with materialThe title compound is dried in vacuo
  2. customBy this method 0.013 g of a red-brown amorph substance are obtained

Sources & evidence

ORD record
ord-05ecec8696f54e14a69ae6682f19d802
Source dataset
uspto-grants-2010_02
Patent number
US07666868B2

Reaction notes

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