反应详情

温度

90 °C

A suspension of 2-chloro-4-fluorobenzaldehyde (24.9 g, 0.16 mol) and dry sodium methanesulfinate (17.9 g, 0.175 mmol) in dry DMSO (60 ml) is stirred at 90° C. overnight. The reaction mixture is allowed to cool to room temperature and then poured onto ice-water (400 ml). The resulting precipitated is collected by filtration and dried under high vacuum to yield the titled compound as a yellow powder.

1. temperatureto cool to room temperature
2. additionpoured onto ice-water (400 ml)
3. customThe resulting precipitated
4. filtrationis collected by filtration
5. customdried under high vacuum