참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Chloro-4-fluorobenzaldehyde | HCID 145024 | — |
| 반응물 | Sodium methanesulfinate | HCID 2733271 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 2-Chloro-4-(methylsulfonyl)benzaldehyde | HCID 2761084 | — |
반응 단계
A suspension of 2-chloro-4-fluorobenzaldehyde (24.9 g, 0.16 mol) and dry sodium methanesulfinate (17.9 g, 0.175 mmol) in dry DMSO (60 ml) is stirred at 90° C. overnight. The reaction mixture is allowed to cool to room temperature and then poured onto ice-water (400 ml). The resulting precipitated is collected by filtration and dried under high vacuum to yield the titled compound as a yellow powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07666878B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_02 |
|---|
| ORD ID | ord-b5a05e877778479e85d4511b615722ee |
|---|
| 출처 메모 | uspto-grants-2010_02 |
|---|
