Hydrochloric Acid → 2-Methyl-4-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione

HRID 1445669Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.Cl.[O-:12][Mn](=O)(=O)=O.[K+].[CH3:18][N:19]=[C:20]=[O:21]>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:9](=[O:12])[S:10][N:19]([CH3:18])[C:20]2=[O:21])=[CH:4][CH:3]=1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 12149p-Tolyl isothiocyanate

HCID 12228Methyl Isocyanate

HCID 516875Potassium Permanganate

Product 1

HCID 65391462-Methyl-4-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione

Procedure

Reagents: 4-Methylphenyl isothiocyanate (0.88 ml, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), methyl isocyanate (0.38 ml, 6.5 mmol).

Sources & evidence

ORD record: ord-d070456b4e6044e3bf0eee9a2c2d0e82
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666885B2

Reaction notes

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