Water → N-[3-(dimethylamino)propyl]-5-iodo-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide
Reaction equation
[C:23]([c:24]1[nH:25][cH:26][cH:27][n:28]1)([c:29]1[nH:30][cH:31][cH:32][n:33]1)=[O:34].[CH3:35][N:36]([CH2:37][CH2:38][CH2:39][NH2:40])[CH3:41].[I:1][c:2]1[cH:3][c:4]([C:20](=[O:21])[OH:22])[c:5](=[O:19])[n:6](-[c:9]2[cH:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]2)[c:7]1[CH3:8].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47].[OH2:42]>>[I:1][c:2]1[cH:3][c:4]([C:20](=[O:21])[NH:40][CH2:39][CH2:38][CH2:37][N:36]([CH3:35])[CH3:41])[c:5](=[O:19])[n:6](-[c:9]2[cH:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]2)[c:7]1[CH3:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-45ff919bb43a4ed288e623717aa870dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…