HRID1445778

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1514340

tert-Butyl (3R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate

C10H19NO3

HCID2734690

Sulfur, trifluoro[2-methoxy-N-(2-methoxyethyl)ethanaminato-.kappa.N]-, (T-4)-

C6H14F3NO2S

HCID18453464

tert-Butyl (3S)-3-fluoropyrrolidine-1-carboxylate

C9H16FNO2

PRODUCTS

生成物

HCID58951460

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Prepare using the method of Intermediate 48 with (R)-N-Boc-pyrrolidine-3-methanol (0.50 g, 2.48 mmol), [bis(2-methoxyethyl)amino]sulfur trifluoride (0.55 mL, 2.98 mmol) and anhydrous dichloromethane (2.5 mL) to give the title compound as a colourless oil (0.34 g): MS (m/e): 226 (M+23).

WORKUP

后处理

customPrepare