反应详情

Prepare using the method of Intermediate 49 with p-toluenesulfonic acid monohydrate (0.304 g, 1.87 mmol), tert-butyl (3R)-3-(fluoromethyl)pyrrolidine-1-carboxylate (See Intermediate 56) (0.325 g, 1.87 mmol) and ethanol (2 mL) to give the title compound as a white solid (0.421 g): MS (m/e): 104 (M+1).

1. customPrepare