HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-1,3-thiazole hydrochloride → HCID 58951447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-1,3-thiazole hydrochloride | HCID 2763289 | — |
| Reactant | HCID 135487319 | HCID 135487319 | — |
| Product | HCID 58951447 | HCID 58951447 | — |
Reaction Steps
The title compound is prepared in a manner substantially similar to Intermediate 16 from 2-[2-(4-Hydroxy-phenyl)-5-methyl-oxazol-4-yl]-1-(2-(R)-methyl-pyrrolidin-1-yl)-ethanone (See Intermediate 62) and 4-(chloromethyl)thiazole hydrochloride except KI (1.5 eq.) is also added. MS (ES+) 398.3
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666871B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-a6b26266c827410eb67c942c71949816 |
| Source note | uspto-grants-2010_02 |