4-(Methanesulfonyl)phenylboronic acid → 2-(4'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Participants

Role	Name	HCID	Charge
Reactant	4-(Methanesulfonyl)phenylboronic acid	HCID 2734364	—
Reactant	2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole	HCID 11681546	—
Product	2-(4'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole	HCID 11560594	—

Reaction Steps

Starting with 2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole (See Example 8) and 4-methylsulfonylphenylboronic acid, follow a procedure significantly analogous to that found in Example 22 to give the titled compound. MS (m/e): 411.2 (M+1)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07666871B2
Source dataset	uspto-grants-2010_02
ORD ID	ord-4e52a9de71f041b6b4d6d05881eb067d
Source note	uspto-grants-2010_02