2-Methylpyrrolidine → HCID 11530951, compound

HRID 1445820Notes

Reaction equation

[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:21][CH2:22]O.[CH3:24][CH:25]1[CH2:29][CH2:28][CH2:27][NH:26]1>>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[CH:9][C:10]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH2:21][CH2:22][N:26]1[CH2:27][CH2:28][CH2:29][CH:25]1[CH3:24]

Participants

Reactant 2

HCID 130032-Methylpyrrolidine

HCID 58951441HCID 58951441, compound

Product 1

HCID 11530951HCID 11530951, compound

Procedure

2-(4-{5-Methyl-4-[2-(2-methyl-pyrrolidin-1-yl)-ethyl]-oxazol-2-yl}-phenoxymethyl)-pyridine is prepared in a manner substantially similar to Example 53 from 2-{5-Methyl-2-[4-(pyridin-2-ylmethoxy)-phenyl]-oxazol-4-yl}-ethanol and 2-methylpyrrolidine. MS (m/e): 378.3 (M+1)

Sources & evidence

ORD record: ord-3edd65954b4648a79a9fa6a099545983
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666871B2

Reaction notes

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