Ethanol → HCID 135487319, compound

Participants

Reaction Steps

A mixture of 2-(4-Benzyloxy-phenyl)-5-methyl-4-[2-(2-(R)-methyl-pyrrolidin-1-yl)-ethyl]-oxazole (See Example 55) (0.48 g, 1.3 mmol) and 5% Pd/C (0.046 g) in absolute ethanol (25 mL) is shaken under a hydrogen atmosphere (65 psi) for 18 h. The mixture is filtered and concentrated to provide the title compound (0.35 g, 94%) as a yellow oil, which was used without purification. MS (m/e): 287.3 (M+1)

Provenance & Evidence