Dichloromethane → 5-(3-Aminopropyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

HRID 144616Notes

Reaction equation

HRID 144616 reaction equation
[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32].[NH2:1][c:2]1[n:3][c:4]([NH:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[c:5]([CH2:9][CH2:10][CH2:11][NH:12][C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[c:6]([CH3:8])[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([NH:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[c:5]([CH2:9][CH2:10][CH2:11][NH2:12])[c:6]([CH3:8])[n:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86633392tert-Butyl 3-(2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)propylcarbamate

Product 1

HCID 98378705-(3-Aminopropyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-2eb0720e213845d5a9f4cf792ccfb7c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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