Diethylamine → HCID 24809891, compound

HRID 1446165Notes

Reaction equation

HRID 1446165 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:12][N:11]=[CH:10][C:9]=1[C:13]([OH:15])=O.[CH2:16]([NH:18][CH2:19][CH3:20])[CH3:17]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:12][N:11]=[CH:10][C:9]=1[C:13]([N:18]([CH2:19][CH3:20])[CH2:16][CH3:17])=[O:15]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 224942765-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid

Product 1

HCID 24809891HCID 24809891, compound

Procedure

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and diethylamine (4.4 mg, 0.060 mmol) as described in synthetic method A and thereafter purified by preparative HPLC method A to give a solid (3.8 mg). MS (pos) m/z 279.1 (M+1).

Workup

  1. custompurified by preparative HPLC method A

Sources & evidence

ORD record
ord-f7661e5d7bc54fb89cc9ac75a735702d
Source dataset
uspto-grants-2010_02
Patent number
US07666888B2

Reaction notes

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