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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446177Generated: November 2, 2026

4-(Trifluoromethoxy)benzylamine → HCID 24809929, compound

https://huagongshe.com/reaction/1446177

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)benzylamineHCID 571846—
Reactant5-(3-Chlorophenyl)-isoxazole-4-carboxylic acidHCID 22831695—
ProductHCID 24809929HCID 24809929—

Reaction Steps

The title compound was prepared from 5-(3-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 4-(trifluoromethoxy)benzylamine (11.5 mg, 0.060 mmol) as described in synthetic method A and thereafter purified by preparative HPLC method B to give a solid (4.5 mg). MS (pos) m/z 397.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-2e455710aeaf4a9aaf73ac55e9b8362b
Source noteuspto-grants-2010_02