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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446180Generated: November 2, 2026

3-(Trifluoromethyl)piperidine → HCID 24809958, compound

https://huagongshe.com/reaction/1446180

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)piperidineHCID 2760776—
Reactant5-(p-Tolyl)isoxazole-4-carboxylic acidHCID 22831706—
ProductHCID 24809958HCID 24809958—

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and DL-3-(trifluoromethyl)piperidine (9.2 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (11.2 mg). HRMS calcd for C17H17F3N2O2: 338.1242, found 338.1242.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-a0e4a34903cb49528d3a40e66f614bb6
Source noteuspto-grants-2010_02