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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446183Generated: October 31, 2026

4-Phenylpiperidin-4-ol → HCID 24809960, compound

https://huagongshe.com/reaction/1446183

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Phenylpiperidin-4-olHCID 96387—
Reactant5-(p-Tolyl)isoxazole-4-carboxylic acidHCID 22831706—
ProductHCID 24809960HCID 24809960—

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 4-hydroxy-4-phenylpiperidine (10.6 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (3.9 mg). HRMS calcd for C22H22N2O3: 362.1630, found 362.1623.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-2b368c88a7204c87b89c66a5ed659394
Source noteuspto-grants-2010_02