Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446186Generated: November 2, 2026

4-(Trifluoromethyl)piperidine hydrochloride → HCID 24809985, compound

https://huagongshe.com/reaction/1446186

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)piperidine hydrochlorideHCID 16218160—
Reactant5-(p-Tolyl)isoxazole-4-carboxylic acidHCID 22831706—
ProductHCID 24809985HCID 24809985—

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 4-(trifluoromethyl)piperidine hydrochloride (9.2 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (8.5 mg). Calcd for C17H17F3N2O2: 338.1242, found 338.1238.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-9d3d6e6556654a5da9468f1bdcc7b27f
Source noteuspto-grants-2010_02