HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Difluoropiperidine hydrochloride → HCID 24810017, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Difluoropiperidine hydrochloride | HCID 2758349 | — |
| Reactant | 5-(p-Tolyl)isoxazole-4-carboxylic acid | HCID 22831706 | — |
| Product | HCID 24810017 | HCID 24810017 | — |
Reaction Steps
The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3,3-difluoropiperidine hydrochloride (9.5 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (4.4 mg). Calcd for C16H16F2N2O2: 306.1180, found 306.1177.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-ece69187a4844135b0e97ec646ef6e77 |
| Source note | uspto-grants-2010_02 |