HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)-4-hydroxypiperidine → HCID 24810018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)-4-hydroxypiperidine | HCID 38282 | — |
| Reactant | 5-(p-Tolyl)isoxazole-4-carboxylic acid | HCID 22831706 | — |
| Product | HCID 24810018 | HCID 24810018 | — |
Reaction Steps
The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 4-(4-chlorophenyl)-4-hydroxypiperidine (12.7 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (8.2 mg). Calcd for C22H21ClN2O3: 396.1241, found 396.1239.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-eb4ea6b8f53e4004a6368f75c8a10680 |
| Source note | uspto-grants-2010_02 |