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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446198Generated: November 2, 2026

1-(2-Pyrimidinyl)piperazine → HCID 24810019, compound

https://huagongshe.com/reaction/1446198

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
Reactant5-(p-Tolyl)isoxazole-4-carboxylic acidHCID 22831706—
ProductHCID 24810019HCID 24810019—

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 1-(2-pyrimidyl)piperazine (9.9 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (4.4 mg). Calcd for C19H19N5O2: 349.1539, found 349.1538.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-9e40ff4ed4a3416ebacd4bd83c12be82
Source noteuspto-grants-2010_02