HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1) → HCID 59170061, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1) | HCID 17749754 | — |
| Reactant | 5-(p-Tolyl)isoxazole-4-carboxylic acid | HCID 22831706 | — |
| Product | HCID 59170061 | HCID 59170061 | — |
Reaction Steps
The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3-(4-fluorobenzyl)pyrrolidine hydrochloride (12.9 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (6.3 mg). Calcd for C22H21FN2O2: 364.1587, found 364.1604.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-ea9a82d2ec0b44dab798be83c9f891c6 |
| Source note | uspto-grants-2010_02 |