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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446214Generated: November 2, 2026

3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1) → HCID 59170061, compound

https://huagongshe.com/reaction/1446214

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1)HCID 17749754—
Reactant5-(p-Tolyl)isoxazole-4-carboxylic acidHCID 22831706—
ProductHCID 59170061HCID 59170061—

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3-(4-fluorobenzyl)pyrrolidine hydrochloride (12.9 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (6.3 mg). Calcd for C22H21FN2O2: 364.1587, found 364.1604.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-ea9a82d2ec0b44dab798be83c9f891c6
Source noteuspto-grants-2010_02