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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446230Generated: November 3, 2026

3-(Trifluoromethyl)piperidine → HCID 59170045, compound

https://huagongshe.com/reaction/1446230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)piperidineHCID 2760776—
Reactant5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acidHCID 22494276—
ProductHCID 59170045HCID 59170045—

Reaction Steps

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and DL-3-(trifluoromethyl)piperidine (9.2 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (11.6 mg). Calcd for C16H14ClF3N2O2: 358.0696, found 358.0702.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-6d31dfe7e565484e8ed1c81317cb3c51
Source noteuspto-grants-2010_02