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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446235Generated: November 2, 2026

3-[4-(Trifluoromethyl)benzyl]pyrrolidine oxalate → HCID 59170056, compound

https://huagongshe.com/reaction/1446235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[4-(Trifluoromethyl)benzyl]pyrrolidine oxalateHCID 17998818—
Reactant5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acidHCID 22494276—
ProductHCID 59170056HCID 59170056—

Reaction Steps

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 3-[4-(trifluoromethyl)benzyl]pyrrolidine oxalate (19.2 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (9.2 mg). Calcd for C22H18ClF3N2O2: 434.1009, found 434.1003.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-8ac42fb714f945278638b1f050a115c8
Source noteuspto-grants-2010_02