HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyrrolidin-3-yl)pyridine → 3-(1-{[5-(2-Chlorophenyl)isoxazol-4-yl]carbonyl}pyrrolidin-3-yl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyrrolidin-3-yl)pyridine | HCID 3613651 | — |
| Reactant | 5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid | HCID 22494276 | — |
| Product | 3-(1-{[5-(2-Chlorophenyl)isoxazol-4-yl]carbonyl}pyrrolidin-3-yl)pyridine | HCID 59170065 | — |
Reaction Steps
The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 3-pyrrolidin-3-ylpyridine (8.9 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (8.0 mg). Calcd for C19H16ClN3O2: 353.0931, found 353.0932.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-a5a242eda8f04967ad2f61357d0fe1c9 |
| Source note | uspto-grants-2010_02 |