HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Ethyl-2-methylpiperidine → 1-{[5-(2-Chlorophenyl)isoxazol-4-yl]carbonyl}-5-ethyl-2-methylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Ethyl-2-methylpiperidine | HCID 7727 | — |
| Reactant | 5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid | HCID 22494276 | — |
| Product | 1-{[5-(2-Chlorophenyl)isoxazol-4-yl]carbonyl}-5-ethyl-2-methylpiperidine | HCID 59170169 | — |
Reaction Steps
The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 5-ethyl-2-methylpiperidine (7.6 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (2.8 mg). Calcd for C18H21ClN2O2: 332.1292, found 332.1293.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-84d0e09911444e619d73e2709d7a725a |
| Source note | uspto-grants-2010_02 |