HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)piperidine → HCID 59170226, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)piperidine | HCID 2760776 | — |
| Reactant | 4-Isoxazolecarboxylic acid, 5-[4-(trifluoromethyl)phenyl]- | HCID 68682921 | — |
| Product | HCID 59170226 | HCID 59170226 | — |
Reaction Steps
The title compound was prepared from 5-(4-trifluoromethylphenyl)isoxazole-4-carboxylic acid (12.9 mg, 0.050 mmol) and DL-3-(trifluoromethyl)piperidine (9.2 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (11.8 mg). Calcd for C17H14F6N2O2: 392.0959, found 392.0959.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-c6cd6f61f8b24a0fa247e3e052fc7846 |
| Source note | uspto-grants-2010_02 |