HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R)-2-(Methoxymethyl)pyrrolidine → HCID 59170049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R)-2-(Methoxymethyl)pyrrolidine | HCID 671216 | — |
| Reactant | 4-Isoxazolecarboxylic acid, 5-[4-(trifluoromethyl)phenyl]- | HCID 68682921 | — |
| Product | HCID 59170049 | HCID 59170049 | — |
Reaction Steps
The title compound was prepared from 5-(4-trifluoromethylphenyl)isoxazole-4-carboxylic acid (12.9 mg, 0.050 mmol) and (R)-2-methoxymethyl-pyrrolidine (6.9 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (10.1 mg). Calcd for C17H17F3N2O3: 354.1191, found 354.1190.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-738752d06f6b4c928c5a547bdffc22b6 |
| Source note | uspto-grants-2010_02 |